Forskolin Powder CAS No. 66575-29-9

Product Description

Forskolin is a chemical found in the roots of the plant Plectranthus barbatus (Coleus forskohlii). This plant has been used since ancient times to treat heart disorders such as high blood pressure and chest pain (angina), as well as respiratory disorders such as asthma.

Forskolin is a herbal supplement which can be used as a natural remedy for treatment in cancer, obesity, glaucoma, allergies and asthma, heart failure, intestinal spasms, painful cramps during period (dysmenorrhea), irritable bowel syndrome, urinary tract infection, high blood pressure (hypertension), chest pain (angina), difficulty falling asleep (insomnia) and convulsions. Small clinical studies indicate obesity reduction potential as well as asthma prevention.

Forskolin activates the enzyme adenylyl cyclase and increases intrace llular levels of cAMP. cAMP is an important second messenger necessary for the proper biological response of ce lls to hormones and other extrace llular signals. It is required for ce ll communication in the hypothalamus/pituitary gland axis and for the feedback control of hormones via induction of corticotropin-releasing factor gene transcription. Cyclic AMP acts by activating cAMP-sensitive pathways such as protein kinase A and EPAC1.