Welcome to Our Company
Send Inquiry
Amlodipine besylate
Product Details:
X
Amlodipine besylate Price And Quantity
- 1 kg Kilograms
- INR
Amlodipine besylate Trade Information
- mumbai
- Cheque Telegraphic Transfer (T/T) Paypal
- 100 Kilograms kg Per Week
- 1 Week
- Western Europe Australia North America Eastern Europe Middle East Africa Central America South America Asia
- All India
Product Description
| CAS number |
| 88150-42-9 |
| Chemical Formula |
| C20H25ClN2O5 |
| For the treatment of hypertension and chronic stable angina.Amlodipine decreases arterial smooth muscle contractility and subsequent vasoconstriction by inhibiting the influx of calcium ions through L-type calcium channels. Calcium ions entering the cell through these channels bind to calmodulin. Calcium-bound calmodulin then binds to and activates myosin light chain kinase (MLCK). Activated MLCK catalyzes the phosphorylation of the regulatory light chain subunit of myosin, a key step in muscle contraction. Signal amplification is achieved by calcium-induced calcium release from the sarcoplasmic reticulum through ryanodine receptors. Inhibition of the initial influx of calcium decreases the contractile activity of arterial smooth muscle cells and results in vasodilation. The vasodilatory effects of amlodipine result in an overall decrease in blood pressure. Amlodipine is a long-acting CCB that may be used to treat mild to moderate essential hypertension and exertion-related angina (chronic stable angina). Another possible mechanism is that amlodipine inhibits vascular smooth muscle carbonic anhydrase I activity causing cellular pH increases which may be involved in regulating intracelluar calcium influx through calcium channels. |
Enter Buying Requirement Details
Other Products in 'Bulk drugs- API-Pharmaceutical Raw material.' category
Send Inquiry
Send SMS
Call Me FreeKAVYA PHARMA
GST : 24AOKPV4993D2ZG
GST : 24AOKPV4993D2ZG
- Shop No - 215, 2nd Floor, Aaimata Road, Raj Mandir Complex, Parvat Patiya, Surat - 395010, Gujarat, India
- Phone : 08045479081
- Ms. Kavya (Proprietor)
- Mobile : 08045479081
-
sales@kavyapharma.com
KAVYA PHARMA
All Rights Reserved.(Terms of Use)
Developed and Managed by Infocom Network Private Limited.
Developed and Managed by Infocom Network Private Limited.
