10-DAB III exists as white to off-white powder having melting point between 229-239C. The drug intermediate is freely soluble in Dimethyl formamide and Dimethyl sulphoxide, soluble in Methanol, slightly soluble in Ethanol (95%) and Acetone, insoluble in Water, Ethyl acetate, Chloroform, Dichloromethane, Acetonitrile, aq. HCl and aq. NaOH solutions. 10-Deacetylbaccatin III (10-DAB III) is used as an API intermediate in the preparation of the anti-cancer drugs - Paclitaxel, Docetaxel and Cabazitaxel.
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